Dr. Jhon ArmandSimon

June 14, 2008

Survey questions and radiographies resonances for low back pain

Filed under: Health, Pain — admin @ 9:03 am

The routine use of expensive X-rays, MRI and CT in patients with low back pain would be unnecessary and, in the case of two of these reviews, exposes people to radiation, researchers said.

Back pain is one of the most common reasons for consulting the doctor and sick leave.

Experts say that while most patients had no serious condition that is causing the pain, doctors often order immediately imaging procedures that can detect problems such as herniated disks, muscle injuries, arthritis or fractures.

Dr. Roger Chou, of the Oregon Health and Science University in Portland, and colleagues evaluated the results of six studies that included 1,800 people with pain in his lower back or lumbar spine.

Patients who had no signs of a serious underlying cause but as a control immediately received no imaging did better than those for which standard treatment was applied but without imaging studies, the authors wrote in The Lancet.

The results correspond to the particular type of back pain which is usually evaluated by a physician, said the team. The authors urged doctors not to order x-rays, CT or resonances unless concrete signs of a problem.

The controls are often expensive imaging and x-rays and scans expose patients to low doses of radiation may be carcinogenic, the researchers added.

“If there are warning signs that indicate a serious cause of low back pain, the images are rarely helpful in guiding treatment,” said Dr. Michael Koch, University of Goettingen in Germany, who wrote a commentary accompanied the study.

“The images of routine checks for patients with pain in his lower back is a waste of resources for medical care,” added Koch. He also stressed that the controls for images “have some potentially serious side effects.”

“Exposure to radiation is a major public health issue, particularly in women, where controls for images of the lumbar spine to expose the ovaries to radiation,” said Koch.

Meanwhile, the expert noted that although not involved exposure to radiation, the MRI is very expensive.

“Some doctors perform a routine of the lumbar spine or without a clear indication that possibly point to reassure their patients and themselves, to meet the expectations of the patient on diagnostic tests, or other reasons, wrote the computer .

Patients who insist on being subjected to imaging procedures should be counseled about their usefulness in certain limited cases.

June 11, 2008

n humans, the mother’s diet may influence the design of fetal sex

Filed under: Health, Sex — admin @ 2:02 am

“Everything that exists in the Universe
is the result of chance and necessity
(Jacques Monod, 1970
quoting Democritus)

“The sociobiology review
the biological basis
social behavior
in all types
organisms ”
(Edward. O. Wilson)

An article published in the April number of this year in a prestigious scientific journal, the Proceedings of the Royal Society of Biological Sciences, has had an impact on the daily headlines that could be described as global. The conclusion of a rigorous epidemiological study, conducted in a population of mothers in the UK universities of Exeter and Oxford, is that the fetal sex is associated with the characteristics of the diet consumed by the mother immediately before and after the time at which it occurs conception when a sperm fertilizes the egg: the more calories it is rich in the diet (and especially when consuming cereal at breakfast) is more likely to conceive a male fetus. As a result of this finding, the authors believe to be low calorie diets, prevalent today in young women in industrialized countries, which would explain the slow decline in the number of births of sons.

This finding may be read, no doubt, as an argument for the influence of the biological behaviors in humans, in the context of evolutionary biology, rooted in Darwinian evolution, and also the kind of sociobiology, as define, in 1975, the American zoologist and entomologist Edward O. Wilson, a discipline on the borderline between anthropology, life sciences and sociology, which studies the interaction between biological systems and the evolution of social behavior, and how and to what extent these social behaviors are listed in the genes, even in humans (Wilson, EO Sociobiology: The New Synthesis, 25 Anniversary Edition, Harvard University Press, 2000).

One of the most active areas of sociobiology is that studies in nonhuman mammals, the biological basis of the ratio between males and females in offspring, seen as the set of children who have a birth animals. ” The hypotheses that have attempted to answer this question, the best known and controversial is the proposal published in the journal Science, in 1973, two scientists from Harvard, Robert sociobiólogo. L. Trivers and mathematician Dan Willard.

The Trivers-Willard hypothesis suggests that the physiological condition of the mother influences the sex of their offspring: mothers whose physiological condition is good, because they live in areas with ample food resources, gestarían more male offspring, whereas mothers whose physiological is poor, because they live in areas short of food, females have more offspring.

This theory, from the perspective of evolutionary biology, predicts that mothers with different physiological conditions with biologically in their pregnancies, the proportion of male offspring / female (sex ratio “or ratio between the sexes in the offspring) in connection with future reproductive benefits of the flock in the environment in which they live: if the environment is favorable, with abundant food that allow mothers to maintain good physiological condition, males predominate in the offspring, as they can reproduce more (andalusia inseminate more and females have more offspring), but if the environment is poor in resources, and physiological condition of the mother is poor, the pups are females, mostly.

The application of the Trivers-Willard hypothesis to humans has been and is controversial because theoretical, empirical and ideological. New Zealand’s Elissa Cameron, an evolutionary biologist who has worked in Australia and South Africa, currently at the University of Nevada at Reno, has recently contributed to the analysis of the Trivers-Willard hypothesis by analyzing nearly 1,000 studies that had subjected to experimental verification. In his review (Proceedings of the Royal Society of London, 2004) found that 34% of the published studies had data that favored the Trivers-Willard hypothesis, at 8.5% did not favor the data, while in the rest found no evidence for or against.

In a previous study in this review, conducted by the Elissa Cameron with wild horses in Australia, concluded that the physical condition of the mother when the concept is associated, significantly, with the birth of a male or a female. In his view, body fat and diet might affect glucose levels in maternal circulation, thus suggesting that these glucose levels at the time of conception could influence the sex of the animal conceived, so excess glucose that favor males.

Working at the University of Pretoria in South Africa, Cameron set out to prove through experiments in mice, the theory of the influence of maternal diet on the sex of the offspring. The experimental method used was adding dexamethasone, which reduces levels of blood glucose, water to drink to be 20 female mice, using as many females who do not drink this water as controls. During three days in cages made for male mice copulate with females with the following results: females with low levels of blood glucose, because they had drunk water with dexamethasone, gave birth to litters with 42% of males, compared with females that had not been drunk, with high levels of blood glucose, with 52% of males in their litters.

That is, under certain conditions, Darwinian natural selection would favor deviations in either direction, which is considered typical division of the sex of the offspring, half female, half male sex andalusia encourage better reproduced in poor physical condition, which is the feminine, and that mothers in poor physiological condition still can find some male insemination while the male weakened more difficult to find a female to mate.

“Would you like a child? Take cereal for breakfast” is the title of a commentary on the magazine’s ScienceNOW Daily News 23 April 2008, which analyzes the findings of researchers from Exeter and Oxford, and their relationships with the hypothesis sociobiológica of Trivers and Willard, in which, even accepting that these results are the first to appear in favor of this hypothesis, however, not clear that the nutrition of the mother is the most important cause of progressive decline in the number of children in developed countries, and is likely to coexist with other factors have also been implicated as environmental pollution.

Anyway, what can not be overlooked is the unfathomable complexity of the biological background of certain human behaviors, so partial to findings, although relevant from the standpoint of sociobiology, it must avoid any temptation too reductionist, understood here as an oversimplification of what is, in itself, is very complicated.

June 7, 2008

Fourth death from bird flu in China this year

Filed under: Bird Flu, Health, news — admin @ 10:57 am

A woman of 31 years is the fourth fatality from the bird flu virus in humans since the beginning of the year, confirmed by the Department of Health of the western Chinese region of Xinjiang.

The deceased, a resident of the regional capital, Urumqi, died at dawn on Friday. According to the department’s regional deputy director, Wang Xiaoyan, the victim was at a live poultry market before falling ill on January 10.

Analysis of the Center for Disease Control today confirmed the presence of the lethal H5N1 virus of avian influenza in samples taken from the victim.

Since January 5 Three other people died in China on avian flu: a rural immigrant 19 years in Beijing the same day, last Saturday of another woman 27 years in Shandong (east) and 20 a couple days of 16 years in the central province of Hunan.

A baby of two years who was admitted to the province of Shanxi on avian flu was discharged from hospital yesterday after he threatened to leave and remained stable for six days straight.

The short space of time that these deaths have been recorded in China, where since 2003 there were 34 cases of which 22 died, has triggered alarms to a possible mutation of the H5N1 strain that allows the transmission between humans and not only from infected birds to people.

This theory took power after it was known that the mother of the baby Shanxi died two weeks ago of ‘pneumonia’, a symptom of bird flu, whose presence could not be confirmed because the body was cremated.

According warned the World Health Organization (WHO) on several occasions, infections occur among people with the disease could become a pandemic for which there is no vaccine.

Data updated on Thursday, the WHO since 2003 indicate there have been 399 cases of bird flu in people in 15 countries, most of Southeast Asia, of whom 251 died.

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